Innovative diagnostic and therapeutic approaches in potassium channel developmental and epileptic encephalopathies (K-DEEs) using 4P for medicine.
Pr. Rima Nabbout
Rima Nabbout has been a professor of Paediatric Neurology since 2014, and the director of the National Centre for Rare Epilepsies since 2006 at Necker-Enfants Malades Hospital. She received a MD in 1990, a Ph.D. in Neurosciences in 2003, and a « Habilitation à Diriger des Recherches » (Accreditation to supervise research) in 2010. More recently, she holds a research and academic position at Imagine Institute in the team “Translational Research for Neurological Diseases” where she leads the epilepsy research program.
News
Expanding the phenotypic and genotypic spectrum of KCNT1-related epilepsies
Gras M., Quentin-Romand G., Chemaly N., Barcia G., KCNT1 consortium, Nabbout R., Brain Communications, 2026 https://doi.org/10.1093/braincomms/fcag256 Abstract The KCNT1 gene encodes for a sodium-activated potassium […]
Revealing Intermediate States of Voltage-Gated Potassium Channels with Physics-Informed Deep Learning: Application to Kv7.1
Kacher J., Tarek M., Frontiers in Biophysics, 2026 https://www.frontiersin.org/journals/biophysics/articles/10.3389/frbis.2026.1877588/abstract Abstract Voltage-gated potassium channels convert changes in membrane voltage into pore opening through conformational […]
Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals
Scorrano G., Breuillard D., Thimon A., Chemaly N., Nabbout R., Epilepsia Open, 2026 https://doi.org/10.1002/epi4.70247 Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and […]
