Innov4-ePiK - Therapies for rare epilepsies

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Innov4-ePiKInnov4-ePiK articlesPublications

Publications

The Innov4-ePiK project’s publications highlight the scientific advancements and key contributions made through its work. Discover articles, reports, and other communication presenting the research outcomes from our program and related to the partners.

posted on 8 July 2026 Publications

Expanding the phenotypic and genotypic spectrum of KCNT1-related epilepsies

Gras M., Quentin-Romand G., Chemaly N., Barcia G., KCNT1 consortium, Nabbout R., Brain Communications, 2026 https://doi.org/10.1093/braincomms/fcag256 Abstract The KCNT1 gene encodes for a sodium-activated potassium [...]

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posted on 23 June 2026 Publications

Revealing Intermediate States of Voltage-Gated Potassium Channels with Physics-Informed Deep Learning: Application to Kv7.1

Kacher J., Tarek M., Frontiers in Biophysics, 2026 https://www.frontiersin.org/journals/biophysics/articles/10.3389/frbis.2026.1877588/abstract Abstract Voltage-gated potassium channels convert changes in membrane voltage into pore opening through conformational [...]

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posted on 21 May 2026 Publications

Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals

Scorrano G., Breuillard D., Thimon A., Chemaly N., Nabbout R., Epilepsia Open, 2026 https://doi.org/10.1002/epi4.70247 Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and [...]

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posted on 3 March 2026 Publications

Training-Free Graph-Based Imputation of Missing Modalities in Multimodal Recommendation

Malitesta D., Rossi E., Pomo C., Di Noia T., Malliaros F. D., IEEE Transactions on Knowledge and Data Engineering, 2026 [...]

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posted on 1 September 2025 Publications

ADMP-GNN: Adaptive Depth Message Passing GNN

Abbahaddou Y., Malliaros FD., Lutzeyer JF. Vazirgiannis M. https://arxiv.org/abs/2509.01170 Abstract Graph Neural Networks (GNNs) have proven to be highly effective in various graph [...]

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posted on 6 June 2025 Publications

Graph Neural Network Generalization with Gaussian Mixture Model Based Augmentation

Abbahaddou, Y., Malliaros, F. D., Lutzeyer, J. F., Aboussalah, A. M., & Vazirgiannis, M. https://arxiv.org/html/2411.08638v3 Abstract Graph Neural Networks (GNNs) have shown great [...]

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posted on 7 May 2025 Publications

kcnb1 loss of function in zebrafish causes neurodevelopmental and epileptic disorders associated with γ-aminobutyric acid dysregulation

Robichon L., Bar C., Marian A., Lehmann L., Renault S., Kabashi E., Ciura S., Nabbout R., Epilepsia, 2025 https://doi.org/10.1111/epi.18407 Abstract Objective KCNB1 encodes an α-subunit [...]

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posted on 7 April 2025 Publications

Embracing the future: Neonatal screening for epileptic syndromes

Nabbout R., Kuchenbuch M., Epilepsia, 2025 https://doi.org/10.1111/epi.18285

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posted on 11 November 2024 Publications

Transition from pediatric to adult care system in patients with complex epilepsies: Necker model for transition evaluated on 70 consecutive patients

Nabbout R., Molimard A., Scorrano G., Aubart M., Breuillard D., Delaune M., Barcia G., Chemaly N., Barthez M-A., Desguerre I., [...]

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This work benefited from a government grant managed by the Agence Nationale de la Recherche (ANR) under the 4th PIA,
integrated into France 2030 with the reference ANR-23-RHUS-0002.

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